Description

Pamoic Acid CAS NO 130-85-8 is an organic dicarboxylic acid widely recognized for its ability to form stable, water-insoluble salts (pamoates) with various basic compounds. This property is commercially valuable for creating long-acting, depot formulations in the pharmaceutical industry. It serves as a critical intermediate and salt-forming agent for manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors seeking to modify the solubility and release profiles of active ingredients.

Application

• Pharmaceutical Salt Formation: Primary use in synthesizing pamoate salts of basic drugs (e.g., antipsychotics, anthelmintics) to create sustained-release injectable or oral formulations.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key building block in the multi-step synthesis of complex drug molecules.
• Agrochemical Industry: Used in the development of prodrugs or salt forms of pesticides and herbicides to enhance stability or efficacy.
• Research & Development: Employed in preclinical and clinical research for drug discovery and formulation studies.
• Fine Chemical Synthesis: Acts as a specialty reagent in organic synthesis for introducing specific functional groups.
• Chemical Standard: Utilized as a high-purity reference standard for analytical testing and quality control laboratories.

Basic Information

Product Name	Pamoic Acid
CAS No.	130-85-8
Molecular Formula	C23H16O6
Molecular Weight	388.37 g/mol
Synonyms	4,4'-Methylenebis(3-hydroxy-2-naphthoic acid); Embonic Acid; 2-Hydroxy-3-naphthoic acid methylene dimer; 4,4'-Methylenedi(3-hydroxy-2-naphthoic acid); 3,3'-(Methylenebis(4,1-naphthylene))bis(2-hydroxyacrylic acid) (obsolete); PAM acid; Pamoate acid
EINECS	204-998-5

Quality Control

Our Pamoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to yellow-brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.