Description

(5Z)-7-[(1α,4α)-3β-[(1E,3S)-3-Hydroxy-1-Octenyl]-7-Oxabicyclo[2.2.1]Heptane-2α-Yl]-5-Heptenoic Acid is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its precise stereochemistry and structural complexity, which are critical for biological activity studies. It is primarily sought by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of prostaglandin-based drugs and other bioactive molecules.
• Biochemical Research: Used as a reference standard and a key reagent in studies of eicosanoid pathways, inflammation, and cellular signaling.
• Drug Discovery & Development: Serves as a core scaffold for medicinal chemistry programs aimed at developing new treatments for cardiovascular, ocular, and inflammatory conditions.
• Academic Research: Employed in university and institutional labs for investigating the structure-activity relationships (SAR) of complex lipid mediators.
• Process Chemistry: Utilized in the development and scale-up of synthetic routes for complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(5Z)-7-[(1α,4α)-3β-[(1E,3S)-3-Hydroxy-1-Octenyl]-7-Oxabicyclo[2.2.1]Heptane-2α-Yl]-5-Heptenoic Acid
CAS No.	82337-14-2
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	9-Deoxy-9-methylene-16,16-dimethyl PGE2; 9-Deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; 16,16-Dimethyl-9-deoxy-9-methylene-PGE2; 9-Methylene-16,16-dimethyl-9-deoxy-PGE2; (5Z)-7-[(1R,2R,3R,5S)-3-[(1E,3S)-3-Hydroxy-1-octen-1-yl]-7-oxabicyclo[2.2.1]heptan-2-yl]-5-heptenoic Acid; Prostaglandin E2 analog; PGE2 derivative
EINECS	Contact for details

Quality Control

Our (5Z)-7-[(1α,4α)-3β-[(1E,3S)-3-Hydroxy-1-Octenyl]-7-Oxabicyclo[2.2.1]Heptane-2α-Yl]-5-Heptenoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and stereochemical integrity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support research and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.