Description

Methyl 3-Bromo-2-Methoxy-2-Methylpropanoate is a specialized brominated ester building block of significant value in advanced organic synthesis. Its unique structure, featuring both bromine and methoxy functional groups, makes it a versatile intermediate for constructing complex molecules. This compound is particularly sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a brominated, branched ester moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its reactive bromine atom facilitates further functionalization.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to introduce complex ester-containing fragments.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced materials with tailored properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and labeled compounds for biochemical and pharmacological research.

Basic Information

Product Name	Methyl 3-Bromo-2-Methoxy-2-Methylpropanoate
CAS No.	82270-54-0
Molecular Formula	C7H13BrO3
Molecular Weight	225.08 g/mol
Synonyms	3-Bromo-2-methoxy-2-methylpropanoic acid methyl ester; Methyl 3-bromo-2-methoxyisobutyrate; 2-Methoxy-2-methyl-3-bromopropionic acid methyl ester; 3-Bromo-2-methoxy-2-methylpropionic acid methyl ester; Methyl α-methoxy-β-bromoisobutyrate; β-Bromo-α-methoxyisobutyric acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Bromo-2-Methoxy-2-Methylpropanoate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 2°C and 8°C for extended stability, although the product is stable at controlled room temperature for shorter periods. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.