Description

14-Deoxyandrographoside is a bioactive diterpenoid lactone, a key constituent derived from the medicinal plant *Andrographis paniculata*. This compound is valued for its role as a chemical reference standard and a crucial intermediate in pharmaceutical research and development. It is primarily utilized by research institutions, analytical laboratories, and manufacturers in the pharmaceutical and nutraceutical sectors for quality control, metabolic studies, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification of related compounds in herbal extracts and finished products via analytical techniques like HPLC and LC-MS.
• Biochemical Research: Serves as a critical intermediate or probe in studying the biosynthesis, metabolism, and structure-activity relationships (SAR) of andrographolide and its derivatives.
• Nutraceutical Quality Control: Employed to standardize and authenticate Andrographis paniculata extracts, ensuring product consistency and efficacy for dietary supplements.
• Pharmaceutical Intermediate: Acts as a starting material or precursor in the semi-synthesis of novel diterpenoid analogs with potential enhanced pharmacological profiles.
• Academic Research: Utilized in university and institutional labs for pharmacological screening and investigating potential anti-inflammatory, hepatoprotective, or antiviral mechanisms.

Basic Information

Product Name	14-Deoxyandrographoside
CAS No.	82209-72-1
Molecular Formula	C₂₀H₃₀O₅
Molecular Weight	350.45 g/mol
Synonyms	14-Deoxyandrographolide; 3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; Neoandrographolide (Note: Often confused, but a distinct isomer); Andrographis Diterpene; 14-Deoxy-11,12-didehydroandrographolide (incorrect but common alias); 14-Deoxyandrographis compound
EINECS	Contact for details

Quality Control

Our 14-Deoxyandrographoside is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.