Description

3-Pentafluorophenyl-Propionaldehyde is a high-value fluorinated organic building block characterized by its reactive aldehyde group attached to a pentafluorophenyl moiety. This compound matters for its unique electronic properties and stability, making it an essential intermediate in advanced synthetic chemistry. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in protease inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in creating advanced, fluorinated pesticides and herbicides with enhanced biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies.
• Polymer Modification: Incorporates fluorine into polymer backbones to alter surface properties, chemical resistance, and thermal stability.
• Cross-Coupling Reactions: Acts as an electrophile in Pd-catalyzed reactions like Suzuki-Miyaura couplings for biaryl formation.
• Ligand & Catalyst Development: Used to synthesize novel fluorinated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Pentafluorophenyl-Propionaldehyde
CAS No.	82208-42-2
Molecular Formula	C9H5F5O
Molecular Weight	224.13 g/mol
Synonyms	3-(Pentafluorophenyl)propanal; 3-(Perfluorophenyl)propionaldehyde; Pentafluorophenylpropionaldehyde; 3-Pentafluorophenylpropanal; 3-(2,3,4,5,6-Pentafluorophenyl)propanal; 82208-42-2; 3-PFP-propionaldehyde; γ-Oxo-3-(pentafluorophenyl)propane
EINECS	Contact for details

Quality Control

Our 3-Pentafluorophenyl-Propionaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.5%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.