Description

3-Chloro-5-Fluoro-2-Hydroxybenzaldehyde is a versatile halogenated aromatic aldehyde that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents adjacent to a formyl and a phenolic hydroxyl group, makes it a highly valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by manufacturers of specialty dyes and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in antimicrobial, anti-inflammatory, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and pesticides where the halogen atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Functional Dye and Pigment Manufacturing: Intermediate for producing specialized dyes, optical brighteners, and photoactive materials.
• Material Science Research: Building block for polymers and organic electronic materials requiring specific halogenated aromatic units.
• Chemical Research & Development: A versatile reagent for exploring new organic reactions and synthesizing complex heterocyclic compounds.

Basic Information

Product Name	3-Chloro-5-Fluoro-2-Hydroxybenzaldehyde
CAS No.	82128-69-6
Molecular Formula	C7H4ClFO2
Molecular Weight	174.56 g/mol
Synonyms	2-Hydroxy-3-chloro-5-fluorobenzaldehyde; 3-Chloro-5-fluorosalicylaldehyde; 5-Fluoro-3-chloro-2-hydroxybenzaldehyde; 3-Chloro-5-fluoro-2-hydroxybenzenecarboxaldehyde; Salicylaldehyde, 3-chloro-5-fluoro-; 3-Chloro-5-fluorosalicylic aldehyde; 2-Formyl-6-chloro-4-fluorophenol
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluoro-2-Hydroxybenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global clientele in research and production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.