Description

(2R)-2-[(2S,5S)-5-Ethenyl-5-Methyl-Oxolan-2-Yl]Propanal is a high-purity chiral aldehyde building block of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined structure, which is crucial for imparting specific biological activity and sensory properties in final products. This compound is primarily needed by R&D and production chemists in the pharmaceutical, agrochemical, and specialty fragrance industries for the synthesis of complex, optically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or with specific stereochemical requirements.
• Agrochemical Synthesis: Used in the development of novel, enantiomerically pure pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Flavor & Fragrance (F&F) Ingredient: Serves as a building block for creating sophisticated, natural-identical aroma chemicals and flavor compounds with unique olfactory profiles.
• Asymmetric Catalysis Research: Employed as a standard or substrate in the development and testing of new chiral catalysts and methodologies.
• Fine Chemical Production: Integral to the multi-step synthesis of other high-value specialty chemicals used in electronics, materials science, and diagnostics.

Basic Information

Product Name	(2R)-2-[(2S,5S)-5-Ethenyl-5-Methyl-Oxolan-2-Yl]Propanal
CAS No.	81967-88-6
Molecular Formula	C11H18O2
Molecular Weight	182.26 g/mol
Synonyms	(2R)-2-[(2S,5S)-5-Ethenyl-5-Methyltetrahydrofuran-2-yl]propanal; (2R,2'S,5'S)-5'-Ethenyl-5'-Methyl-2'-propionyltetrahydrofuran; 2-[(2S,5S)-5-Ethenyl-5-methyloxolan-2-yl]propanal (enantiomer); Chiral Tetrahydrofuran Aldehyde; 81967-88-6; (2R)-2-[(2S,5S)-5-Vinyl-5-methyltetrahydrofuran-2-yl]propanal
EINECS	Contact for details

Quality Control

Our (2R)-2-[(2S,5S)-5-Ethenyl-5-Methyl-Oxolan-2-Yl]Propanal is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with full specification data are provided with each shipment to guarantee traceability and compliance with your internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. For long-term storage, keep the container in a cool, dry, and well-ventilated area. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.