Description

6-(Bromomethyl)-1-Naphthonitrile is a versatile brominated naphthalene derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its reactive bromomethyl group adjacent to the electron-withdrawing nitrile functionality makes it a valuable building block for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those with naphthalene-based scaffolds, for therapeutic areas such as oncology and CNS disorders.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the naphthonitrile core can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials due to its rigid, planar structure.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or affinity probes for studying biological systems and target engagement.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl systems.

Basic Information

Product Name	6-(Bromomethyl)-1-Naphthonitrile
CAS No.	81940-37-6
Molecular Formula	C12H8BrN
Molecular Weight	246.10 g/mol
Synonyms	1-Naphthonitrile, 6-(bromomethyl)-; 6-Bromomethyl-1-naphthonitrile; 1-Cyano-6-(bromomethyl)naphthalene; 6-(Bromomethyl)naphthalene-1-carbonitrile; (6-Bromomethyl-naphthalen-1-yl)-acetonitrile; 81940-37-6; 6-Bromomethyl-1-cyanonaphthalene
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Standard quality parameters include identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. Certificates of Analysis (COA) detailing specific results are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.