Description

Diethyl 2-[4-(Chlorobenzoyl)Amino]Malonate is a high-purity, versatile chemical intermediate characterized by its malonate ester and chlorobenzamide functional groups. This compound matters for its critical role in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research and development. It is primarily needed by manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and fine chemical industries for constructing heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those with heterocyclic cores.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its reactive malonate moiety.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other specialty chemicals requiring precise molecular architecture.
• Peptidomimetics Research: Employed in medicinal chemistry for the design and synthesis of peptide-like molecules.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical reactions in organic synthesis.

Basic Information

Product Name	Diethyl 2-[4-(Chlorobenzoyl)Amino]Malonate
CAS No.	81918-01-6
Molecular Formula	C14H16ClNO5
Molecular Weight	313.73 g/mol
Synonyms	Diethyl (4-chlorobenzamido)malonate; 2-[(4-Chlorobenzoyl)amino]propanedioic acid diethyl ester; Diethyl 2-[(4-chlorobenzoyl)amino]malonate; Propanedioic acid, 2-[(4-chlorobenzoyl)amino]-, diethyl ester; Diethyl (4-chlorobenzamido)malonate; 81918-01-6; Malonic acid, (p-chlorobenzamido)-, diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl 2-[4-(Chlorobenzoyl)Amino]Malonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. The material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.