Description

Methyl 2-[Acetyl-(4-Aminophenyl)Sulfonyl-Amino]Acetate is a specialized organic intermediate featuring a sulfonamide linkage and an acetyl-protected amino group, making it a valuable synthon for constructing complex molecular architectures. Its core value lies in its bifunctional reactivity, which facilitates its use in the synthesis of advanced pharmaceutical compounds and high-performance materials. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients or functional additives.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including protease inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides that utilize the sulfonylurea or sulfonamide pharmacophore.
• Dye & Pigment Manufacturing: Serves as a precursor for creating specialized azo dyes and pigments, leveraging the 4-aminophenyl group for color development.
• Polymer Modification: Employed to introduce sulfonamide functional groups into polymer chains to alter solubility, thermal stability, or biological activity.
• Chemical Research: A versatile reagent in academic and industrial laboratories for exploring new organic reactions and methodologies involving sulfonamides.
• Material Science: Potential use in the development of advanced materials such as metal-organic frameworks (MOFs) or functional coatings.

Basic Information

Product Name	Methyl 2-[Acetyl-(4-Aminophenyl)Sulfonyl-Amino]Acetate
CAS No.	81865-31-8
Molecular Formula	C11H14N2O5S
Molecular Weight	286.31 g/mol
Synonyms	Methyl N-acetyl-N-(4-aminophenylsulfonyl)glycinate; Acetamide, N-[(4-aminophenyl)sulfonyl]-N-(carboxymethyl)-, methyl ester; Methyl {[acetyl(4-aminophenyl)sulfonyl]amino}acetate; N-Acetylsulfanilylglycine Methyl Ester; Glycine, N-(acetylsulfanilyl)-, methyl ester; 2-[(Acetyl-(4-aminophenyl)sulfonyl)amino]acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for fine chemical intermediates. Every batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We adhere to a cGMP-compliant quality management system to ensure reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.