Description

1-(2-Methyl-4-Oxo-Pentan-2-Yl)-3-[(2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6- (Hydroxymethyl)Oxan-2-Yl]Thiourea is a sophisticated thiourea derivative characterized by a glucose moiety linked to a branched ketone chain. This unique molecular architecture makes it a valuable intermediate for advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting glycosidase enzymes or requiring carbohydrate-based pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that leverage its thiourea and sugar-based structure for bioactivity.
• Bioconjugation & Chemical Biology: Acts as a versatile linker or reagent for modifying biomolecules (proteins, peptides) due to the reactive thiourea group and the hydrophilic sugar unit.
• Catalyst & Ligand Synthesis: Employed in the preparation of chiral ligands or organocatalysts for asymmetric synthesis, where the multiple stereocenters can induce selectivity.
• Glycochemistry & Glycomimetics: A crucial precursor for creating complex glycomimetics, glycoconjugates, or analogs of natural glycosides for biological studies.
• Material Science Research: Investigated for potential use in creating functionalized polymers or smart materials with specific molecular recognition properties.

Basic Information

Product Name	1-(2-Methyl-4-Oxo-Pentan-2-Yl)-3-[(2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6- (Hydroxymethyl)Oxan-2-Yl]Thiourea
CAS No.	81827-18-1
Molecular Formula	C14H26N2O6S
Molecular Weight	350.43 g/mol
Synonyms	N-(2-Methyl-4-oxopentan-2-yl)-N'-(β-D-glucopyranosyl)thiourea; 1-(2-Methyl-4-oxopentan-2-yl)-3-β-D-glucopyranosylthiourea; β-D-Glucopyranosyl-1-(2-methyl-4-oxopentan-2-yl)thiourea; Thiourea, N-(2-methyl-4-oxopentan-2-yl)-N'-(β-D-glucopyranosyl)-; Glucosyl thiourea derivative (ketone-substituted); (2R,3R,4S,5S,6R)-2-[3-(2-Methyl-4-oxopentan-2-yl)thioureido]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
EINECS	Contact for details

Quality Control

Our production of 1-(2-Methyl-4-Oxo-Pentan-2-Yl)-3-[(2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6- (Hydroxymethyl)Oxan-2-Yl]Thiourea adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We operate under a cGMP-compliant quality management system, ensuring traceability and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when required. For long-term storage, consider inert atmosphere protection to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.