Description

L-Tyrosine, 2,5-Dibromo- CAS NO 81818-46-4 is a halogenated derivative of the essential amino acid L-Tyrosine, serving as a critical synthetic intermediate and building block in advanced organic chemistry. This compound is valued for its role in introducing bromine functional groups, which are pivotal for modifying molecular properties and enabling further chemical transformations. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceutical development, agrochemical synthesis, and the creation of specialized biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for tyrosine kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and plant growth regulators where the brominated tyrosine moiety influences biological activity.
• Biochemical Probe Synthesis: Essential for creating labeled compounds and molecular probes for studying enzyme mechanisms and protein interactions in biochemical research.
• Peptide Modification: Employed to introduce bromine atoms into peptide chains, altering their stability, receptor binding affinity, and metabolic profile for peptide-based drug discovery.
• Material Science Precursor: Acts as a monomer or precursor for synthesizing specialized polymers and advanced organic materials with unique electronic or structural properties.
• Academic & Industrial R&D: Serves as a versatile reagent in organic synthesis laboratories for method development and exploring new chemical reactions.

Basic Information

Product Name	L-Tyrosine, 2,5-Dibromo-
CAS No.	81818-46-4
Molecular Formula	C9H9Br2NO3
Molecular Weight	338.98 g/mol
Synonyms	2,5-Dibromo-L-tyrosine; (2S)-2-Amino-3-(2,5-dibromo-4-hydroxyphenyl)propanoic acid; L-2,5-Dibromotyrosine; H-2,5-Dibromo-Tyr-OH; 2,5-Dibromo-4-hydroxyphenylalanine; Tyrosine, 2,5-dibromo-; Brominated L-Tyrosine derivative
EINECS	Contact for details

Quality Control

Our L-Tyrosine, 2,5-Dibromo- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and chiral analysis to confirm enantiomeric integrity. We provide Certificates of Analysis (COA) with detailed results for parameters such as assay, impurity profile, and specific rotation. Our quality commitment ensures material consistency for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.