Description

4-tert-Butylbiphenyl-3-Carboxylic Acid is a high-purity, functionalized biphenyl derivative that serves as a critical synthetic intermediate. Its value lies in the combination of the robust biphenyl scaffold with a carboxylic acid group and a bulky tert-butyl substituent, enabling precise control over molecular geometry and reactivity. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and liquid crystal compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Liquid Crystal Materials: Serves as a core structural unit for creating advanced liquid crystal mixtures used in displays (LCDs) and optical devices.
• Organic Synthesis: Utilized in coupling reactions and as a precursor for more complex polycyclic aromatic structures in material science.
• Agrochemical Research: Acts as an intermediate in the development of new generation herbicides and plant growth regulators.
• Polymer Additives: Can be incorporated into polymer chains to modify thermal stability and optical properties.
• Ligand Synthesis: Used to prepare specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-tert-Butylbiphenyl-3-Carboxylic Acid
CAS No.	81770-19-6
Molecular Formula	C₁₇H₁₈O₂
Molecular Weight	254.33 g/mol
Synonyms	3'-tert-Butylbiphenyl-4-carboxylic Acid; 4'-tert-Butyl-[1,1'-biphenyl]-3-carboxylic Acid; 3-Carboxy-4'-tert-butylbiphenyl; 4-(1,1-Dimethylethyl)-[1,1'-biphenyl]-3-carboxylic Acid; 4-tert-Butyl-3-biphenylcarboxylic Acid; NSC 403119; Biphenyl-3-carboxylic acid, 4'-tert-butyl-
EINECS	Contact for details

Quality Control

Every batch of 4-tert-Butylbiphenyl-3-Carboxylic Acid is produced under strict quality management protocols. We ensure compliance with relevant industry standards through rigorous in-process and final release testing, including identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and product integrity for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert gas purging to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	165 - 170 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.