Description

Anistreplasa [Inn-Spanish] is a thrombolytic agent, a modified form of human tissue plasminogen activator (t-PA) designed for the treatment of acute myocardial infarction. This pharmaceutical active ingredient is critical for its ability to rapidly dissolve blood clots, restoring blood flow to the heart muscle. It is primarily required by pharmaceutical manufacturers and research institutions developing or producing advanced cardiovascular and thrombolytic therapies.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of injectable thrombolytic drugs for acute coronary syndromes.
• Cardiovascular Research: Used as a reference standard or experimental compound in preclinical and clinical studies investigating fibrinolysis.
• Biosimilar Development: Serves as a critical reference molecule for companies developing biosimilar versions of thrombolytic agents.
• Hospital & Clinical Pharmacy: For compounding or preparation in specialized clinical settings, under strict regulatory oversight.
• Biotechnology Manufacturing: Utilized in processes for the production of related recombinant protein therapeutics.

Basic Information

Product Name	Anistreplasa [Inn-Spanish]
CAS No.	81669-57-0
Molecular Formula	C₂₅₈₀H₃₉₈₈N₇₈₀O₇₉₀S₄₀ (Approximate for protein)
Molecular Weight	~65-70 kDa (Approximate)
Synonyms	Anistreplase; Eminase; p-Anisoylated Lys-Plasminogen Streptokinase Activator Complex; APSAC; BRL-26921; Anistreplasa (Spanish INN); Anistreplase (USAN, BAN); Plasminogen Activator, p-Anisoylated
EINECS	Contact for details

Quality Control

Our Anistreplasa is produced and controlled under a strict quality management system. Each batch is subjected to a comprehensive battery of analytical tests to ensure identity, purity, potency, and safety, meeting the stringent requirements for a biopharmaceutical active substance. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature of 15-25°C or under refrigerated conditions at 2-8°C as specified for the specific lyophilized formulation. The product is hygroscopic (moisture-sensitive) and must be protected from humidity. For long-term stability, store in the original sealed container under the recommended conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (Biological Activity)	≥ 90.0% to 110.0% of labeled potency
Purity (SDS-PAGE / SEC-HPLC)	≥ 95.0%
Protein Content	By UV absorbance or other suitable method
Residual Moisture (KF)	≤ 3.0%
Bacterial Endotoxins	< 10 EU/mg
Sterility	Sterile (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.