Description

Ketanserinol is a selective serotonin receptor antagonist with significant research and pharmacological interest. This compound is a key intermediate in the synthesis of more complex active pharmaceutical ingredients (APIs) and serves as a vital reference standard in analytical chemistry. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and chemical manufacturers focused on neuropharmacology and cardiovascular drug development. Ketanserinol CAS NO 76330-73-9 is valued for its high purity and reliable performance in critical synthetic and analytical workflows.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of serotonin receptor-targeting active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a selective pharmacological tool to study serotonin (5-HT) receptor subtypes and their functions in neurological and cardiovascular systems.
• Reference Standard: Serves as a high-purity analytical standard for method development, validation, and quality control in HPLC, LC-MS, and other chromatographic assays.
• Academic Studies: Employed in university and institutional research projects investigating receptor-ligand interactions and signal transduction pathways.
• Drug Discovery & Development: A key compound in preclinical research for screening and developing new therapeutic agents targeting serotonin pathways.

Basic Information

Product Name	Ketanserinol
CAS No.	76330-73-9
Molecular Formula	C22H22FN3O3
Molecular Weight	395.43 g/mol
Synonyms	Ketanserinol; 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4(1H,3H)-quinazolinedione; R 53 333; R-53333; R53333; Ketanserinol tartrate salt; 4'-Fluorobenzoyl ketanserinol
EINECS	Contact for details

Quality Control

Our Ketanserinol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.