Description

(S)-1,2-Epoxydecane CAS NO 81623-66-7 is a high-purity chiral epoxide building block of significant value in asymmetric synthesis. Its enantiomerically pure structure makes it a critical intermediate for the production of optically active pharmaceuticals, agrochemicals, and specialty materials. This compound is essential for research and development chemists and process engineers in the fine chemical, pharmaceutical, and advanced material sectors seeking to introduce specific stereochemistry into target molecules.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Used as a key building block for constructing active pharmaceutical ingredients (APIs) with defined stereochemistry, particularly in antiviral, anticancer, and cardiovascular drug candidates.
• Agrochemical Intermediate: Serves as a precursor for the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators, where the specific (S)-configuration can enhance biological activity and reduce environmental impact.
• Liquid Crystal and Advanced Material Precursor: Employed in the synthesis of chiral dopants for liquid crystal displays (LCDs) and other functional organic materials requiring precise molecular orientation.
• Asymmetric Catalysis Research: A valuable substrate for developing and testing new chiral catalysts and methodologies in academic and industrial R&D laboratories.
• Flavor and Fragrance Ingredient Synthesis: Used to create chiral components for high-value aroma chemicals and flavors where stereoisomerism affects the sensory profile.
• Polymer Modification: Acts as a monomer or cross-linking agent for producing polymers with tailored properties, such as epoxy resins with specific chiral centers.

Basic Information

Product Name	(S)-1,2-Epoxydecane
CAS No.	81623-66-7
Molecular Formula	C₁₀H₂₀O
Molecular Weight	156.27 g/mol
Synonyms	(S)-1,2-Epoxydecane; (S)-Decane, 1,2-epoxy-; (S)-1,2-Epoxydodecane (common misnomer); (2S)-2-Octyloxirane; (S)-(-)-1,2-Epoxydecane; (S)-1,2-Epoxy-n-decane; (S)-Glycidyl hexyl ether (related); Chiral Epoxydecane; (S)-Epoxydecane
EINECS	Contact for details

Quality Control

Our (S)-1,2-Epoxydecane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, GC for purity and solvent residues, and identity confirmation via FT-IR and NMR. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity and prevent potential epoxide ring-opening reactions.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.1%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.