Description

4-Fluorophenyl Methylphenylphosphinate is a specialized organophosphorus compound that serves as a critical intermediate in advanced chemical synthesis. Its value lies in its unique structure, which combines a phosphinate core with fluorinated and aromatic moieties, enabling precise modifications in target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other targeted therapy research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, pesticides, and plant growth regulators requiring fluorinated phosphinate structures.
• Ligand & Catalyst Precursor: Serves as a precursor for chiral or bidentate ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the creation of specialty monomers for flame-retardant polymers or advanced polymeric materials with specific thermal properties.
• Chemical Biology Probes: Useful in the design of activity-based probes for studying enzyme mechanisms, particularly phosphatases and related enzymes.

Basic Information

Product Name	4-Fluorophenyl Methylphenylphosphinate
CAS No.	81542-83-8
Molecular Formula	C₁₃H₁₂FO₂P
Molecular Weight	250.21 g/mol
Synonyms	Methylphenylphosphinic Acid 4-Fluorophenyl Ester; (4-Fluorophenoxy)(methyl)phenylphosphine Oxide; P-Methyl-P-phenyl-P'-(4-fluorophenyl) Phosphinate; 4-Fluorophenyl Methyl(phenyl)phosphinate; Methylphenyl(4-fluorophenoxy)phosphine Oxide; 4-FPMPP; 4-Fluorophenol Methylphenylphosphinate
EINECS	Contact for details

Quality Control

Our production of 4-Fluorophenyl Methylphenylphosphinate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.