Description

4,5,6,7-Tetrafluoro-2-Methyl-1H-1,3-Benzodiazole is a high-value fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring a tetrafluorobenzene ring fused to a methyl-substituted diazole, makes it a critical precursor for developing novel materials with tailored electronic and photophysical properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of new active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the introduction of fluorine atoms can dramatically improve efficacy and environmental profile.
• Organic Electronic Materials: Acts as a fundamental building block for electron-deficient units in organic semiconductors, OLED (Organic Light-Emitting Diode) emitters, and electron transport materials.
• Ligand and Catalyst Development: Employed in the synthesis of novel nitrogen-donor ligands for transition metal catalysis, enabling new reaction pathways in fine chemical manufacturing.
• Fluorinated Dye and Pigment Precursor: Provides the core structure for creating specialized fluorophores and colorants with unique light-absorption and emission characteristics.
• Polymer and Advanced Material Modifier: Incorporated into polymer backbones or as a side-chain modifier to impart specific properties like chemical resistance, thermal stability, or altered solubility.

Basic Information

Product Name	4,5,6,7-Tetrafluoro-2-Methyl-1H-1,3-Benzodiazole
CAS No.	81430-75-3
Molecular Formula	C8H4F4N2
Molecular Weight	204.13 g/mol
Synonyms	2-Methyl-4,5,6,7-tetrafluoro-1H-benzimidazole; 4,5,6,7-Tetrafluoro-2-methylbenzimidazole; 2-Methyl-4,5,6,7-tetrafluoro-1H-1,3-benzodiazole; 4,5,6,7-Tetrafluoro-2-methyl-1H-benzimidazole; Tetrafluoromethylbenzimidazole; TFMBI; 1H-1,3-Benzodiazole, 4,5,6,7-tetrafluoro-2-methyl-
EINECS	Contact for details

Quality Control

Every batch of 4,5,6,7-Tetrafluoro-2-Methyl-1H-1,3-Benzodiazole is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for each lot. We support custom synthesis and can tailor purity grades (from technical to >98% HPLC) to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when working with large quantities to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% (High Purity Grade)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.