Description

17-Hydroxy-28-Nor-5α-Oleana-12-Ene-3,16-Dione is a high-purity, semi-synthetic triterpenoid derivative of oleanolic acid, serving as a critical advanced intermediate in pharmaceutical research and development. This compound is valued for its unique structural framework, which provides a versatile scaffold for synthesizing novel bioactive molecules targeting a range of therapeutic areas. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of anti-inflammatory, antiviral, and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in anti-inflammatory and antiviral research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratory settings.
• Biochemical Research: Investigated for its interaction with various enzymes and receptors in metabolic pathway studies.
• Natural Product Derivative Synthesis: Utilized to create semi-synthetic analogs of natural triterpenoids with enhanced efficacy or reduced toxicity.

Basic Information

Product Name	17-Hydroxy-28-Nor-5α-Oleana-12-Ene-3,16-Dione
CAS No.	81426-90-6
Molecular Formula	C29H42O3
Molecular Weight	438.65 g/mol
Synonyms	17-Hydroxy-28-norolean-12-ene-3,16-dione; 28-Norolean-12-ene-3,16-dione, 17-hydroxy-; 17-Hydroxy-28-nor-5α-olean-12-ene-3,16-dione; 17-Hydroxy-28-norolean-12-en-3,16-dione; 3,16-Dioxo-17-hydroxy-28-norolean-12-ene; Olean-12-ene-3,16-dione, 17-hydroxy-28-nor-
EINECS	Contact for details

Quality Control

Our 17-Hydroxy-28-Nor-5α-Oleana-12-Ene-3,16-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.