Description

D-Asparagine, 3-Fluoro-, (3S)-Rel- (9Ci) is a fluorinated derivative of the amino acid asparagine, specifically engineered with a fluorine atom at the 3-position. This targeted modification is crucial for advanced research in medicinal chemistry and biochemistry, where it serves as a key building block or probe. It is primarily utilized by pharmaceutical R&D teams and academic researchers focused on developing novel bioactive compounds, enzyme inhibitors, and metabolic studies. The introduction of fluorine can significantly alter the physicochemical and biological properties of a molecule, making this compound a valuable tool for structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Serves as a sophisticated building block in the synthesis of fluorinated peptide analogs and potential drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways involving amino acids.
• Proteomics & Peptide Chemistry: Incorporated into custom peptides to study the effects of fluorination on peptide structure, stability, and biological activity.
• Medicinal Chemistry SAR Studies: A critical tool for exploring how fluorination at specific sites influences binding affinity, metabolic stability, and bioavailability.
• Isotope-Labeled Compound Synthesis: Acts as a precursor for the synthesis of more complex, labeled compounds for tracer studies.

Basic Information

Product Name	D-Asparagine, 3-Fluoro-, (3S)-Rel- (9Ci)
CAS No.	81370-25-4
Molecular Formula	C4H7FN2O3
Molecular Weight	150.11 g/mol
Synonyms	(3S)-3-Fluoro-D-asparagine; (3S)-3-Fluoroasparagine; D-3-Fluoroasparagine; (2S)-2-Amino-3-fluoro-3-carbamoylpropanoic Acid; 3-Fluoro-D-asparagine; Rel-(3S)-3-Fluoro-D-asparagine; 81370-25-4; (9CI) D-Asparagine, 3-fluoro-, (3S)-rel-
EINECS	Contact for details

Quality Control

Our D-Asparagine, 3-Fluoro-, (3S)-Rel- (9Ci) is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals, and specifications can be tailored to meet specific research-grade or GMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.