Description

3-Bromo-4-Fluorobenzaldehyde Dimethyl Acetal is a versatile and highly valuable protected aldehyde intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers who require precise control over reactivity in multi-step synthetic pathways, particularly where the aldehyde functionality must be temporarily masked. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty liquid crystals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the halogenated benzaldehyde core provides specific biological activity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystal compounds for display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and light-emitting materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Negishi couplings.
• Fine Chemical Synthesis: A versatile starting material for synthesizing various fluorinated and brominated fine chemicals and dyes.

Basic Information

Product Name	3-Bromo-4-Fluorobenzaldehyde Dimethyl Acetal
CAS No.	81358-65-8
Molecular Formula	C9H10BrFO2
Molecular Weight	249.08 g/mol
Synonyms	1-Bromo-2-Fluoro-4-(Dimethoxymethyl)Benzene; 4-Bromo-3-Fluorobenzaldehyde Dimethyl Acetal; (3-Bromo-4-Fluorophenyl)Dimethoxymethane; Benzene, 1-bromo-2-fluoro-4-(dimethoxymethyl)-; Dimethyl (3-Bromo-4-Fluorobenzylidene) Acetal; α,α-Dimethoxy-3-bromo-4-fluorotoluene
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluorobenzaldehyde Dimethyl Acetal is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The material is sensitive to light and should be handled under appropriate conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.