Description

Methyl 4,4-Dichlorobutanoate is a versatile chlorinated ester intermediate of significant importance in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both an ester group and reactive geminal dichloride, which makes it a key building block for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a butanoate backbone with halogen functionality.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the dichloro moiety can impart specific biological activity.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and condensation reactions to introduce the 4,4-dichlorobutanoate moiety into target molecules.
• Polymer Modifier: Acts as a monomer or cross-linking agent in specialty polymer production, influencing material properties.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for metal complexes and organocatalysts used in asymmetric synthesis.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in academic and industrial laboratories.

Basic Information

Product Name	Methyl 4,4-Dichlorobutanoate
CAS No.	81236-55-7
Molecular Formula	C5H8Cl2O2
Molecular Weight	171.02 g/mol
Synonyms	Methyl 4,4-dichlorobutyrate; 4,4-Dichlorobutanoic Acid Methyl Ester; Butanoic acid, 4,4-dichloro-, methyl ester; Methyl 4,4-dichlorobutanoate; 4,4-Dichlorobutanoate methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4,4-Dichlorobutanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets high-grade specifications for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.28 g/cm³
Refractive Index (n20D)	~1.460

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.