Description

Ethanone, 2,2-Difluoro-1-[4-(Methylthio)Phenyl]- (9Ci) is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoroacetyl group adjacent to a methylthio-substituted aromatic ring, enabling precise molecular construction. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Active Ingredient Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored optical or electronic properties.
• Liquid Crystal & OLED Material Development: Employed in the synthesis of fluorinated components for advanced display and lighting technologies.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, nucleophilic additions, and as a scaffold for constructing complex heterocyclic compounds in academic and industrial R&D.

Basic Information

Product Name	Ethanone, 2,2-Difluoro-1-[4-(Methylthio)Phenyl]- (9Ci)
CAS No.	81170-29-8
Molecular Formula	C9H8F2OS
Molecular Weight	202.22 g/mol
Synonyms	2,2-Difluoro-1-[4-(methylthio)phenyl]ethanone; 4'-(Methylthio)-2,2-difluoroacetophenone; 1-[4-(Methylsulfanyl)phenyl]-2,2-difluoroethanone; 2,2-Difluoro-1-(4-methylsulfanylphenyl)ethanone; 4-Methylthiobenzoyl fluoride; Difluoro(4-methylthiophenyl)methanone; 81170-29-8 (CAS)
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2-Difluoro-1-[4-(Methylthio)Phenyl]- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.