Description

Benzofuran, 4,6-Dichloro-3-Methyl- CAS NO 81078-72-0 is a halogenated benzofuran derivative serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its core value lies in its functionalized aromatic structure, which provides a critical scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on novel active ingredients, particularly in the synthesis of heterocyclic compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated benzofuran core for bioactivity.
• Material Science Precursor: Serves as a monomer or starting material for synthesizing specialized polymers and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and other catalytic transformations to introduce the benzofuran moiety into more complex structures.
• Academic & Institutional R&D: Utilized in universities and research institutes for methodological studies and exploring new chemical spaces in heterocyclic chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, pigments, and other performance chemicals.

Basic Information

Item	Detail
Product Name	Benzofuran, 4,6-Dichloro-3-Methyl-
CAS No.	81078-72-0
Molecular Formula	C9H6Cl2O
Molecular Weight	201.05 g/mol
Synonyms	4,6-Dichloro-3-methylbenzofuran; 3-Methyl-4,6-dichlorobenzofuran; 4,6-Dichloro-3-methyl-1-benzofuran; 1-Benzofuran, 4,6-dichloro-3-methyl-; Dichloromethylbenzofuran
EINECS	Contact for details

Quality Control

Every batch of 4,6-Dichloro-3-Methylbenzofuran is produced under strict quality management and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.