Description

1-[3-(Trifluoromethyl)Phenyl]But-1-En-3-One is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a reactive enone moiety adjacent to a trifluoromethylphenyl group, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic semiconductors and liquid crystal compounds, contributing to improved electronic and optical properties.
• Organic Synthesis & Catalysis: Employed in Michael addition reactions, cycloadditions, and as a substrate for developing new catalytic methodologies in academic and industrial R&D settings.
• Fluorine Chemistry Research: A valuable compound for studying the influence of the trifluoromethyl group on reaction pathways and molecular conformation.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Phenyl]But-1-En-3-One
CAS No.	80992-92-3
Molecular Formula	C11H9F3O
Molecular Weight	214.18 g/mol
Synonyms	3'-Trifluoromethylchalcone; 1-[3-(Trifluoromethyl)phenyl]-3-buten-1-one; 3-Buten-1-one, 1-[3-(trifluoromethyl)phenyl]-; (E)-1-(3-(Trifluoromethyl)phenyl)but-2-en-1-one; 3-Trifluoromethylchalcone; 3'-Trifluoromethyl benzylideneacetone; 1-(3-Trifluoromethylphenyl)-2-buten-1-one
EINECS	Contact for details

Quality Control

Our 1-[3-(Trifluoromethyl)Phenyl]But-1-En-3-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for research and process chemistry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.