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Z-Arg(Mtr)-Oh Cha CAS NO 80745-09-1


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CAS No.:80745-09-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Z-Arg(Mtr)-Oh Cha is a protected arginine derivative, a crucial building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to ensure the integrity and yield of complex peptide sequences. It is primarily utilized in pharmaceutical research and development for the production of therapeutic peptides and in biochemical studies.

Application

  • Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the sequential assembly of peptide chains, particularly where arginine residues are required.
  • Pharmaceutical Intermediates: Serves as a critical raw material in the synthesis of peptide-based active pharmaceutical ingredients (APIs) for various therapeutic areas.
  • Bioconjugation: Used in the modification of proteins and other biomolecules, leveraging the reactive guanidino group after deprotection.
  • Research & Development: An essential reagent in academic and industrial labs for exploring new peptide structures and their biological functions.
  • Custom Peptide Production: Employed by CROs and CDMOs for the manufacture of bespoke peptides for clients in drug discovery and diagnostics.

Basic Information

Product Name Z-Arg(Mtr)-Oh Cha
CAS No. 80745-09-1
Molecular Formula C24H30N4O7S
Molecular Weight 518.58 g/mol
Synonyms Nα-Z-Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine; Z-Arg(Mtr)-OH; Benzyloxycarbonyl-Nω-(4-methoxy-2,3,6-trimethylphenylsulfonyl)-L-arginine; Nα-Carbobenzoxy-Nω-(Mtr)-L-arginine; Z-L-Arg(Mtr)-OH; CBZ-Arg(Mtr)-OH; Nα-Cbz-Nω-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine
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Quality Control

Our Z-Arg(Mtr)-Oh Cha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥98.0%
Optical Rotation -10.0° to -14.0° (c=1 in DMF)
Water Content (KF) ≤1.0%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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