Description

Maleimide, 4-Hydroxy-3-(2-(Pyridyl)-4-Thiazolyl)- is a specialized heterocyclic compound featuring a maleimide core fused with pyridyl and thiazolyl moieties, making it a valuable building block for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique structure enables precise molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-cancer agent research.
• Agrochemical Development: Used in the creation of advanced pesticides and herbicides, leveraging its heterocyclic structure for targeted biological activity.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent for producing high-performance polymers, resins, and coatings with tailored thermal or mechanical properties.
• Bioconjugation Chemistry: The maleimide group is reactive towards thiols, making this compound useful for protein labeling, antibody-drug conjugate (ADC) development, and biomaterial functionalization.
• Organic Electronic Materials: Investigated as a component in the synthesis of organic semiconductors or light-emitting materials due to its conjugated system.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry and organic synthesis for library generation and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Maleimide, 4-Hydroxy-3-(2-(Pyridyl)-4-Thiazolyl)-
CAS No.	80653-76-5
Molecular Formula	C12H7N3O3S
Molecular Weight	273.27 g/mol
Synonyms	4-Hydroxy-3-(2-pyridyl-4-thiazolyl)maleimide; 3-(2-Pyridyl-4-thiazolyl)-4-hydroxymaleimide; 4-Hydroxy-3-(2-pyridinyl-4-thiazolyl)-1H-pyrrole-2,5-dione; 1H-Pyrrole-2,5-dione, 4-hydroxy-3-[2-(2-pyridinyl)-4-thiazolyl]-; 3-(2-Pyridyl-4-thiazolyl)-4-hydroxy-1H-pyrrole-2,5-dione
EINECS	Contact for details

Quality Control

Our Maleimide, 4-Hydroxy-3-(2-(Pyridyl)-4-Thiazolyl)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.