Description

Cyclopropane, 1-Chloro-1-Ethynyl-2,2-Dimethyl- (9Ci) is a specialized cyclopropane derivative featuring a reactive ethynyl group and a chloro substituent, making it a valuable synthon in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries seeking to incorporate strained ring systems and alkyne functionality into novel compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing cyclopropane rings known for metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the cyclopropane moiety can enhance biological activity.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers and specialty materials with unique thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in [3+2] cycloadditions and other ring-forming reactions to construct complex, polycyclic structures in medicinal chemistry.
• Ligand and Catalyst Development: Utilized for creating novel organometallic complexes and chiral ligands for asymmetric catalysis.
• Chemical Biology Probes: Functions as a scaffold for developing molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	Cyclopropane, 1-Chloro-1-Ethynyl-2,2-Dimethyl- (9Ci)
CAS No.	80631-43-2
Molecular Formula	C7H9Cl
Molecular Weight	128.60 g/mol
Synonyms	1-Chloro-1-ethynyl-2,2-dimethylcyclopropane; 2,2-Dimethyl-1-chloro-1-ethynylcyclopropane; 1-Chloro-1-ethynyl-2,2-dimethylcyclopropane; (1-Chloro-1-ethynyl-2,2-dimethyl)cyclopropane; Cyclopropane, 1-chloro-1-ethynyl-2,2-dimethyl-; 80631-43-2 (CAS)
EINECS	Contact for details

Quality Control

Our Cyclopropane, 1-Chloro-1-Ethynyl-2,2-Dimethyl- (9Ci) is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced chemical intermediates, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and stored away from heat, sparks, and open flames. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.