Description

Methyl 2-(3-Bromophenyl)Propanoate CAS NO 80622-53-3 is a specialized brominated aromatic ester that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the combination of the bromine substituent, which offers a versatile handle for further functionalization via cross-coupling reactions, and the methyl ester group, which provides synthetic flexibility. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the bromophenyl moiety is a common structural motif.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of monomers or functional additives for advanced polymers and liquid crystals.
• Chemical Reference Standard: Utilized as a high-purity standard in analytical laboratories for method development and quality control.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and esterification/transesterification reactions.

Basic Information

Product Name	Methyl 2-(3-Bromophenyl)Propanoate
CAS No.	80622-53-3
Molecular Formula	C10H11BrO2
Molecular Weight	243.10 g/mol
Synonyms	Methyl 2-(3-Bromophenyl)propionate; 2-(3-Bromophenyl)propionic Acid Methyl Ester; Methyl α-Methyl-3-bromobenzeneacetate; 3-Bromo-α-methylbenzenacetic Acid Methyl Ester; Methyl (3-Bromophenyl)acetate, α-methyl-; Methyl 2-(3-Bromophenyl)-2-methylacetate; (RS)-Methyl 2-(3-bromophenyl)propanoate; 80622-53-3
EINECS	Contact for details

Quality Control

Our Methyl 2-(3-Bromophenyl)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and chiral integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.