Description

3-Chloro-2-Methylbenzenesulfonyl Chloride is a versatile and reactive organosulfur compound primarily used as a key synthetic intermediate. Its value lies in its dual functionality, where the sulfonyl chloride group serves as an excellent electrophile for constructing sulfonamides and sulfonate esters, crucial in advanced chemical synthesis. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the sulfonyl moiety contributes to biological activity.
• Dyestuff and Pigment Manufacturing: Serves as a precursor in the synthesis of specialty dyes and organic pigments, enabling specific color properties and fastness.
• Polymer Modification: Employed to introduce sulfonyl chloride groups into polymer chains for subsequent functionalization, creating materials with tailored surface properties.
• Chemical Research & Development: A valuable reagent in organic synthesis labs for constructing complex molecules and exploring new reaction pathways.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands and catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	3-Chloro-2-Methylbenzenesulfonyl Chloride
CAS No.	80563-86-6
Molecular Formula	C7H6Cl2O2S
Molecular Weight	225.09 g/mol
Synonyms	2-Methyl-3-chlorobenzenesulfonyl chloride; 3-Chloro-o-toluenesulfonyl chloride; 1-Chloro-2-methyl-3-sulfonylchloridebenzene; Benzenesulfonyl chloride, 3-chloro-2-methyl-; 3-Chloro-2-methylphenylsulfonyl chloride; 2-Methyl-3-chlorophenylsulfonyl chloride; o-Toluenesulfonyl chloride, 3-chloro- derivative
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Methylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture. Store away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.