Description

Ethanone, 2,2-Difluoro-1-(2-Pyridinyl)- (9Ci) is a high-purity fluorinated pyridinyl ketone building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those requiring a difluoromethyl ketone or pyridine moiety for bioactivity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the difluoroacetophenone structure can impart favorable metabolic stability and efficacy.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or organic semiconductors, where fluorine substitution fine-tunes electronic properties.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on incorporating fluorine atoms into complex molecular architectures.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects.

Basic Information

Product Name	Ethanone, 2,2-Difluoro-1-(2-Pyridinyl)- (9Ci)
CAS No.	80459-00-3
Molecular Formula	C7H5F2NO
Molecular Weight	157.12 g/mol
Synonyms	2,2-Difluoro-1-(2-pyridinyl)ethanone; 2',2'-Difluoro-2-pyridyl ketone; 2-Pyridyl difluoromethyl ketone; 1-(Pyridin-2-yl)-2,2-difluoroethan-1-one; 2-Acetylpyridine, 2,2-difluoro-; (2-Pyridyl)difluoromethyl ketone; α,α-Difluoro-2-pyridyl methyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2-Difluoro-1-(2-Pyridinyl)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our commitment to quality supports applications in GMP (Good Manufacturing Practice) environments and research requiring the highest material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.