Description

Benzene, 1-Bromo-2,4-Bis(1,1-Dimethylethyl)- is a specialized brominated aromatic compound characterized by its sterically hindered tert-butyl substituents. This molecular architecture makes it a valuable intermediate and building block in advanced organic synthesis, particularly where controlled reactivity and specific steric effects are required. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring sterically hindered aromatic systems.
• Agrochemical Synthesis: Used in the development and production of advanced herbicides, fungicides, and pesticides where the bromine atom offers a site for further functionalization.
• Ligand and Catalyst Development: Acts as a backbone for creating sophisticated phosphine or nitrogen-based ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of monomers for high-performance polymers, liquid crystals, or organic electronic materials.
• Organic Synthesis Building Block: Provides a versatile platform for cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitutions in complex molecule assembly.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial laboratories.

Basic Information

Item	Details
Product Name	Benzene, 1-Bromo-2,4-Bis(1,1-Dimethylethyl)-
CAS No.	80438-66-0
Molecular Formula	C14H21Br
Molecular Weight	269.22 g/mol
Synonyms	1-Bromo-2,4-di-tert-butylbenzene; 2,4-Di-tert-butyl-1-bromobenzene; 2,4-Di-tert-butylbromobenzene; 2,4-Di-t-butyl-1-bromobenzene; 2,4-Di-tert-butylphenyl bromide; 1-Bromo-2,4-di-t-butylbenzene; 2,4-Bis(1,1-dimethylethyl)-1-bromobenzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-Bromo-2,4-Bis(1,1-Dimethylethyl)- is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.