Description

2-(Difluoromethoxy)-1-Naphthaldehyde is a specialized aromatic aldehyde derivative, distinguished by the presence of a difluoromethoxy substituent on the naphthalene ring system. This unique molecular structure makes it a valuable fluorinated building block for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon for the research and development of new active pharmaceutical ingredients (APIs), where the difluoromethoxy group can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging fluorine chemistry to enhance efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where fluorinated aromatic compounds are critical.
• Fluorine Chemistry Research: An important compound for academic and industrial research focused on incorporating fluorine atoms into complex organic frameworks.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	2-(Difluoromethoxy)-1-Naphthaldehyde
CAS No.	80395-32-0
Molecular Formula	C₁₂H₈F₂O₂
Molecular Weight	222.19 g/mol
Synonyms	1-Naphthaldehyde, 2-(difluoromethoxy)-; 2-(Difluoromethoxy)naphthalene-1-carbaldehyde; 1-Naphthalenecarboxaldehyde, 2-(difluoromethoxy)-; 2-(Difluoromethoxy)-1-naphthalenecarboxaldehyde; 2-Difluoromethoxy-1-naphthaldehyde; 80395-32-0; 2-(Difluoromethoxy)naphthaldehyde
EINECS	Contact for details

Quality Control

Our 2-(Difluoromethoxy)-1-Naphthaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For projects requiring specific regulatory support, we can discuss compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.