Description

4-Bromophenylglyoxal Hydrate is a versatile and reactive brominated aromatic glyoxal derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its bifunctional carbonyl groups, which enable the construction of complex heterocyclic and pharmaceutical intermediates. This high-purity compound is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Heterocyclic Chemistry: Fundamental building block for constructing complex heterocyclic scaffolds like imidazoles, pyrazines, and quinoxalines.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, photoresists, and other functional polymeric materials.
• Bioconjugation Chemistry: Reactive handle for modifying proteins, peptides, and other biomolecules in biochemical research and diagnostic assay development.

Basic Information

Product Name	4-Bromophenylglyoxal Hydrate
CAS No.	80352-42-7
Molecular Formula	C8H7BrO3 • xH2O
Molecular Weight	231.05 (Anhydrous basis)
Synonyms	(4-Bromophenyl)glyoxal Hydrate; 2-Oxo-2-(4-bromophenyl)acetaldehyde Hydrate; 4-Bromo-α-oxobenzeneacetaldehyde Hydrate; 4-Bromobenzoylformaldehyde Hydrate; p-Bromophenylglyoxal Hydrate; 4-Bromophenylglyoxal Monohydrate; 1-(4-Bromophenyl)-1,2-ethanedione Hydrate
EINECS	Contact for details

Quality Control

Every batch of 4-Bromophenylglyoxal Hydrate is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and other relevant spectroscopic and chromatographic methods. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.