Description

Bromodifluoromethyl Phenyl Sulfone is a versatile and highly reactive organofluorine building block, primarily valued for its ability to introduce the bromodifluoromethyl group into target molecules. This compound is essential for synthetic chemists developing novel pharmaceuticals, agrochemicals, and advanced materials due to its unique reactivity profile. It is particularly sought after by R&D departments and production facilities in the fine chemical, pharmaceutical, and agrochemical industries for constructing complex fluorinated intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where fluorination often improves efficacy and environmental profile.
• Material Science: Employed in the development of specialty polymers, liquid crystals, and electronic materials that benefit from fluorine's unique properties.
• Organic Synthesis Reagent: Serves as a versatile reagent for nucleophilic substitution and cross-coupling reactions to incorporate the -CF2Br moiety.
• Fluorinated Building Block: Critical for constructing complex molecules in medicinal chemistry and drug discovery programs targeting various disease areas.
• Chemical Research: Utilized in academic and industrial laboratories for methodological development and exploring new reaction pathways in organofluorine chemistry.

Basic Information

Product Name	Bromodifluoromethyl Phenyl Sulfone
CAS No.	80351-58-2
Molecular Formula	C7H5BrF2O2S
Molecular Weight	271.08 g/mol
Synonyms	α-Bromo-α,α-difluorotoluene-p-sulfone; (Bromodifluoromethyl)phenyl sulfone; Phenylsulfonyldifluorobromomethane; 1-Bromo-1,1-difluoro-1-(phenylsulfonyl)methane; Difluorobromomethyl Phenyl Sulfone; Bromodifluoromethyl Phenyl Sulphone; Benzenesulfonyl Bromodifluoromethane
EINECS	Contact for details

Quality Control

Our Bromodifluoromethyl Phenyl Sulfone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.