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(7S,8R)-1-(4-Hydroxy-3-Methoxyphenyl)-2-[4-(3-Hydroxypropyl)-2,6-Di-Methoxyphenoxy]-1,3-Propanediol CAS NO 80292-57-5


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CAS No.:80292-57-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(7S,8R)-1-(4-Hydroxy-3-Methoxyphenyl)-2-[4-(3-Hydroxypropyl)-2,6-Di-Methoxyphenoxy]-1,3-Propanediol is a high-purity, stereochemically defined lignan derivative with significant biological activity. This compound is valued for its role as a key intermediate and reference standard in advanced pharmaceutical research and development. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical, nutraceutical, and fine chemical sectors for applications in drug discovery and synthesis.

Application

  • Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel therapeutic agents, particularly in cardiovascular and metabolic disease research.
  • Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
  • Biochemical Research: Employed in studies investigating the biological activity, metabolism, and pharmacokinetics of natural lignans and their synthetic analogs.
  • Nutraceutical Development: Serves as a high-purity standard for the characterization and standardization of lignan-containing dietary supplements and functional foods.
  • Academic Research: Utilized in university and institutional labs for chemical, pharmacological, and biosynthetic pathway studies.

Basic Information

Item Detail
Product Name (7S,8R)-1-(4-Hydroxy-3-Methoxyphenyl)-2-[4-(3-Hydroxypropyl)-2,6-Di-Methoxyphenoxy]-1,3-Propanediol
CAS No. 80292-57-5
Molecular Formula C21H28O8
Molecular Weight 408.45 g/mol
Synonyms (7S,8R)-Dihydrodehydrodiconiferyl alcohol; (+)-Lariciresinol; (7S,8R)-Lariciresinol; NSC 407303; Lariciresinol (stereoisomer); 1,3-Propanediol, 1-(4-hydroxy-3-methoxyphenyl)-2-[4-(3-hydroxypropyl)-2,6-dimethoxyphenoxy]-, (7S,8R)-; Dihydrodehydrodiconiferyl alcohol
EINECS Contact for details

Quality Control

Our (7S,8R)-1-(4-Hydroxy-3-Methoxyphenyl)-2-[4-(3-Hydroxypropyl)-2,6-Di-Methoxyphenoxy]-1,3-Propanediol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and purity meet exacting standards. A detailed Certificate of Analysis (COA) providing full chromatographic and spectroscopic data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% (7S,8R)
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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