Description

18α-Glycyrrhizic Acid Ammonium Salt is the ammonium salt derivative of the primary bioactive triterpenoid saponin found in licorice root (Glycyrrhiza glabra). This compound is valued for its enhanced water solubility and stability compared to the free acid form, making it a preferred ingredient in advanced formulations. It serves as a critical raw material for manufacturers in the pharmaceutical, nutraceutical, and personal care industries seeking natural bioactive agents with well-documented anti-inflammatory and soothing properties.

Application

• Pharmaceutical Intermediates: Used in the synthesis of anti-inflammatory, antiviral, and hepatoprotective drugs.
• Nutraceuticals & Dietary Supplements: Incorporated into formulations for digestive health, liver support, and immune system modulation.
• Cosmetics & Skincare: A key active ingredient in creams, lotions, and serums for its soothing, anti-redness, and skin-brightening effects.
• Oral Care Products: Utilized in toothpaste and mouthwash for its anti-plaque and gum-soothing benefits.
• Food & Beverage Additives: Employed as a natural high-potency sweetener and flavor enhancer, often as a substitute for sugar.
• Veterinary Medicine: Applied in animal health products for its therapeutic properties.
• Research & Development: Serves as a standard or reagent in biochemical and pharmacological studies.

Basic Information

Product Name	18α-Glycyrrhizic Acid Ammonium Salt
CAS No.	80287-34-9
Molecular Formula	C42H65NO16 • xH2O
Molecular Weight	839.97 (Anhydrous)
Synonyms	Ammonium Glycyrrhizate; Glycyrrhizic Acid Ammonium Salt; Glycyrrhizin Ammonium; Enoxolone Ammonium Salt; 18β-Glycyrrhetinic Acid 3-O-(2-O-β-D-Glucopyranuronosyl-α-D-glucopyranosiduronic acid) Ammonium Salt; Licorice Extract Ammoniated; NSC 107679; UNII-3C5IY3J37T
EINECS	279-656-8

Quality Control

Our 18α-Glycyrrhizic Acid Ammonium Salt is produced under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for identity, purity, and potency, aligning with standards relevant for pharmaceutical and food-grade applications. Comprehensive Certificates of Analysis (COA) documenting HPLC assay, heavy metals, residual solvents, and microbiological limits are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 8.0%
Residue on Ignition	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Arsenic (As)	≤ 3 ppm
Total Aerobic Microbial Count	≤ 1000 CFU/g
Total Combined Yeasts & Molds	≤ 100 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.