Description

Artemisic Acid is a key organic acid and a crucial biosynthetic precursor in the production of artemisinin and its derivatives. This compound matters significantly for its role in enabling the scalable, cost-effective synthesis of essential antimalarial active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical manufacturers, fine chemical synthesis specialists, and research institutions focused on developing and producing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A critical starting material and biosynthetic precursor for the semi-synthesis of artemisinin, dihydroartemisinin, and other artemisinin-based combination therapy (ACT) drugs.
• Antimalarial Drug Production: Serves as a fundamental building block in commercial manufacturing processes for life-saving antimalarial medications.
• Fine Chemical Synthesis: Used in organic synthesis to construct complex sesquiterpene lactone structures and for research into novel chemical entities.
• Biochemical Research: Employed in studies of the mevalonate-independent pathway (MEP/DOXP pathway) and the biosynthesis of isoprenoids in plants and microorganisms.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for HPLC, GC-MS, or NMR analysis of artemisinin-related substances.
• Academic & Industrial R&D: Fundamental for research programs aimed at optimizing artemisinin yields, developing new synthetic routes, or exploring new biological activities of artemisinin analogs.

Basic Information

Item	Detail
Product Name	Artemisic Acid
CAS No.	80286-58-4
Molecular Formula	C15H22O2
Molecular Weight	234.33 g/mol
Synonyms	Artemisinic Acid; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-Trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene-10-carboxylic Acid; Dihydroartemisinic Acid; (+)-Dihydroartemisinic Acid; QHS Acid; Artemisane-10-carboxylic Acid
EINECS	Contact for details

Quality Control

Our Artemisic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.