Description

Oxo-4-Trifluoromethyl-Phenyl)-Acetonitrile is a high-value, versatile chemical intermediate featuring a trifluoromethylphenyl backbone and a reactive nitrile group. This compound is essential for the synthesis of advanced molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a key strategy for enhancing metabolic stability and biological activity. It serves as a critical building block for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing components in electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Material Research: Employed in the creation of specialty polymers, coatings, and functional materials requiring specific fluorinated aromatic structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	Oxo-4-Trifluoromethyl-Phenyl)-Acetonitrile
CAS No.	80277-40-3
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	2-Oxo-2-[4-(trifluoromethyl)phenyl]acetonitrile; 4-(Trifluoromethyl)benzoyl cyanide; 4-(Trifluoromethyl)phenacyl cyanide; α-Oxo-4-(trifluoromethyl)benzeneacetonitrile; (4-Trifluoromethylbenzoyl)formonitrile; 4-Trifluoromethylbenzoyl cyanide; 4-Cyanocarbonylbenzotrifluoride; 2-(4-Trifluoromethylphenyl)-2-oxoacetonitrile
EINECS	Contact for details

Quality Control

Our Oxo-4-Trifluoromethyl-Phenyl)-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.