Description

1-Fluoro-3-(3-Nitrophenyl)Benzene is a high-purity fluorinated aromatic compound that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a nitro group on separate phenyl rings, makes it an essential intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating fluorinated aromatic cores in electronic materials for displays and lighting applications.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, solubility, and optical properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct biaryl systems.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	1-Fluoro-3-(3-Nitrophenyl)Benzene
CAS No.	80254-72-4
Molecular Formula	C₁₂H₈FNO₂
Molecular Weight	217.20 g/mol
Synonyms	3'-Fluoro-3-nitro-1,1'-biphenyl; 3-Fluoro-3'-nitrobiphenyl; 3-Nitro-3'-fluorobiphenyl; (3-Fluorophenyl)(3-nitrophenyl); 1-Fluoro-3-(3-nitrophenyl)benzene; 3-Fluoro-3'-nitro-1,1'-biphenyl; 3-Nitro-3'-fluorodiphenyl
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-(3-Nitrophenyl)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.