Description

3-Acetamido-2,2-Dimethylpropanoic Acid is a high-purity, specialized organic building block characterized by its unique sterically hindered structure. This compound matters as a versatile intermediate for synthesizing complex molecules where the introduction of a protected amino acid moiety with gem-dimethyl substitution is required. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by fine chemical manufacturers producing advanced materials and custom synthesis products.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly peptides and peptidomimetics with enhanced metabolic stability.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, dyes, and advanced polymer additives.
• Bioconjugation & Linker Chemistry: Utilized in the development of chemical linkers and probes for bioconjugation applications in diagnostics and biochemical research.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	3-Acetamido-2,2-Dimethylpropanoic Acid
CAS No.	80253-47-0
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	3-Acetamido-2,2-dimethylpropionic acid; 2,2-Dimethyl-3-acetamidopropanoic acid; N-Acetyl-3-amino-2,2-dimethylpropionic acid; 3-(Acetylamino)-2,2-dimethylpropanoic acid; Ac-Dmp-OH; (3-Acetamido-2,2-dimethylpropanoyl)oxy; AADA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-Acetamido-2,2-Dimethylpropanoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications requiring high standards, including pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.