Description

Hexanoic Acid, 2-Fluoro-3-Oxo-, Methyl Ester is a specialized fluorinated keto-ester building block with the CAS number 80171-28-4. This compound is valued for its unique molecular structure, which combines a reactive keto group and a fluorine atom on a short-chain ester backbone, making it a versatile intermediate for advanced synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, including potential active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Advanced Material Precursor: Serves as a building block for specialty polymers, liquid crystals, or organic electronic materials requiring specific fluorinated components.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for complex organic transformations, such as nucleophilic substitutions or cyclization reactions facilitated by the reactive keto-ester moiety.
• Fluorine Chemistry Research: An important compound for studying structure-activity relationships (SAR) and the effects of fluorine introduction in molecular scaffolds.

Basic Information

Product Name	Hexanoic Acid, 2-Fluoro-3-Oxo-, Methyl Ester
CAS No.	80171-28-4
Molecular Formula	C7H11FO3
Molecular Weight	162.16 g/mol
Synonyms	Methyl 2-Fluoro-3-oxohexanoate; 2-Fluoro-3-oxohexanoic Acid Methyl Ester; 3-Oxo-2-fluorohexanoic Acid Methyl Ester; Hexanoic acid, 2-fluoro-3-oxo-, methyl ester; Methyl 3-oxo-2-fluorohexanoate; 2-Fluoro-3-oxo-hexanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Hexanoic Acid, 2-Fluoro-3-Oxo-, Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific research or cGMP development requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its highly volatile nature, keep the container tightly sealed when not in use and store away from heat, sparks, and open flame. For long-term storage, consider maintaining the product under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.