Description

4-(3-Hydroxy-1-propyn-1-yl)benzaldehyde (Saltdata: Free) is a versatile aromatic aldehyde derivative featuring a propargyl alcohol substituent. This unique bifunctional structure, containing both an aldehyde and a terminal alkyne with a hydroxyl group, makes it a valuable building block for advanced organic synthesis. It is primarily sought by R&D and production chemists in the pharmaceutical and specialty chemical industries for constructing complex molecular architectures, including heterocycles and chiral intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a benzaldehyde core with a functionalized side chain for further coupling reactions (e.g., Sonogashira, click chemistry).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators where its reactive groups allow for the creation of diverse bioactive structures.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands for metal catalysis or organocatalysts, leveraging the aldehyde and alkyne for imine or triazole formation.
• Material Science Research: Employed in the creation of novel polymers, dendrimers, or metal-organic frameworks (MOFs) through polymerization or coordination reactions involving its functional groups.
• Fine Chemical Production: Utilized in the multi-step synthesis of dyes, flavors, fragrances, and other high-value specialty chemicals requiring precise molecular construction.

Basic Information

Item	Details
Product Name	4-(3-Hydroxy-1-propyn-1-yl)benzaldehyde (Saltdata: Free)
CAS No.	80151-10-6
Molecular Formula	C10H8O2
Molecular Weight	160.17 g/mol
Synonyms	4-(3-Hydroxyprop-1-yn-1-yl)benzaldehyde; 4-(3-Hydroxy-1-propynyl)benzaldehyde; 4-Formylphenyl propargyl ether (tautomeric form); 4-(2-Hydroxyethynyl)benzaldehyde; 4-(3-Hydroxypropynyl)benzaldehyde; p-(3-Hydroxy-1-propynyl)benzaldehyde; Benzaldehyde, 4-(3-hydroxy-1-propyn-1-yl)-
EINECS	Contact for details

Quality Control

Our 4-(3-Hydroxy-1-propyn-1-yl)benzaldehyde is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.