Description

7α,20-Epoxy-6β,7β,15β-Trihydroxykaur-16-En-11-One 6-Acetate is a high-purity diterpenoid derivative, a key intermediate in advanced pharmaceutical synthesis and biochemical research. This compound is valued for its complex, functionalized kaurane skeleton, which serves as a crucial building block for developing novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of complex natural product analogs and bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and metabolic disease research.
• Biochemical Research: Used as a reference standard or a starting material in studies investigating diterpenoid biosynthesis, structure-activity relationships (SAR), and enzyme inhibition.
• Natural Product Synthesis: Serves as a sophisticated chiral building block for the total or semi-synthesis of complex natural products with kaurane or related diterpenoid frameworks.
• Academic & Discovery Chemistry: Employed in university and institutional labs for methodological development in organic synthesis, including studies on epoxide chemistry and selective acetylation.
• Fine Chemical Production: Integrated into the manufacturing process for high-value, specialized fine chemicals used in advanced material science and agrochemical research.

Basic Information

Product Name	7α,20-Epoxy-6β,7β,15β-Trihydroxykaur-16-En-11-One 6-Acetate
CAS No.	80138-59-6
Molecular Formula	C22H30O7
Molecular Weight	406.47 g/mol
Synonyms	6β-Acetoxy-7α,20-epoxy-6β,7β,15β-trihydroxykaur-16-en-11-one; 7α,20-Epoxy-6β,7β,15β-trihydroxykaur-16-en-11-one 6-acetate; Kaur-16-en-11-one, 7α,20-epoxy-6β,7β,15β-trihydroxy-, 6-acetate; (4bS,6aR,6bS,7S,8aS,9R,10aS,10bS)-7-(Acetyloxy)-4b,6a,6b,7,8a,9,10a,10b-octahydro-4b,9-dihydroxy-6b-(hydroxymethyl)-1,1,6a,8a-tetramethyl-5-oxo-5H-naphtho[2,1-a]azulen-9-yl acetate
EINECS	Contact for details

Quality Control

Our 7α,20-Epoxy-6β,7β,15β-Trihydroxykaur-16-En-11-One 6-Acetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and moisture. We provide comprehensive Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.