Description

Methyl 2-([4-Hydroxydihydro-2(3H)-Isoxazolyl]Carbonyl)Benzenecarboxylate is a high-value heterocyclic carboxylic acid ester derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its unique molecular structure, featuring both an isoxazolidinone and a benzoate moiety, makes it essential for constructing complex molecules with targeted biological activity. This compound is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used as a building block for creating advanced herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex heterocyclic frameworks and conducting structure-activity relationship (SAR) studies.
• Material Science Research: Potential monomer or additive in the development of specialty polymers and functional materials.
• Bioconjugation Chemistry: The reactive ester group can be utilized for linking molecules in probe and diagnostic agent development.

Basic Information

Product Name	Methyl 2-([4-Hydroxydihydro-2(3H)-Isoxazolyl]Carbonyl)Benzenecarboxylate
CAS No.	80041-99-2
Molecular Formula	C12H11NO5
Molecular Weight	249.22 g/mol
Synonyms	Methyl 2-((4-hydroxy-2-oxo-2,3-dihydroisoxazol-5-yl)carbonyl)benzoate; Benzoic acid, 2-[(4-hydroxy-2,3-dihydro-5-isoxazolyl)carbonyl]-, methyl ester; 5-(2-Methoxycarbonylbenzoyl)-4-hydroxy-4,5-dihydroisoxazol-3(2H)-one; Methyl 2-(4-hydroxy-2-oxo-2,3-dihydroisoxazole-5-carbonyl)benzoate; Isoxazolidinone benzoate derivative; CAS 80041-99-2.
EINECS	Contact for details

Quality Control

Our production of Methyl 2-([4-Hydroxydihydro-2(3H)-Isoxazolyl]Carbonyl)Benzenecarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles verified by HPLC, GC, NMR, and MS. Our quality system is designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.