Description

(E)-Methyl 3-Aminobut-2-Enoate is a versatile β-amino acrylate ester, a crucial building block in organic synthesis. Its unique structure, featuring both an amino and an ester functional group on a conjugated alkene, makes it a valuable precursor for constructing complex heterocycles and pharmaceutical intermediates. This high-purity compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of β-amino acids, peptides, and various nitrogen-containing heterocycles like pyrimidines and pyridines, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create compounds with specific biological activity.
• Fine Chemical Building Block: Serves as a versatile starting material for the preparation of specialty chemicals, dyes, and functionalized polymers requiring precise molecular architecture.
• Academic & Industrial Research: Employed in method development and discovery chemistry for studying Michael addition reactions, cycloadditions, and other transformations central to modern organic synthesis.
• Material Science Precursor: Potential use in the synthesis of monomers for advanced polymeric materials with tailored properties.

Basic Information

Product Name	(E)-Methyl 3-Aminobut-2-Enoate
CAS No.	80012-11-9
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	Methyl (E)-3-aminobut-2-enoate; Methyl 3-amino-2-butenoate; (E)-3-Amino-2-butenoic acid methyl ester; 3-Aminocrotonic acid methyl ester; Methyl 3-aminocrotonate; β-Aminocrotonic acid methyl ester; 2-Butenoic acid, 3-amino-, methyl ester, (2E)-; Methyl β-aminocrotonate
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-Aminobut-2-Enoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee reliable performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
(E)-Isomer Content	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.