Description

1,3-Diphenyl-1,1,3,3-Tetramethyldisilazane is a high-purity organosilicon compound that serves as a versatile reagent and protecting group in advanced synthetic chemistry. Its primary value lies in its role as a selective silylating agent, enabling the protection of sensitive functional groups and facilitating complex multi-step syntheses. This chemical is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for process development and scale-up.

Application

• Pharmaceutical Intermediate Synthesis: Used as a key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for protecting alcohols and amines during complex reaction sequences.
• Agrochemical Production: Employed in the manufacture of advanced pesticides and herbicides where selective silylation is required to control reactivity and improve yields.
• Polymer & Material Science: Acts as a precursor or modifying agent in the development of silicone-based polymers, resins, and advanced materials with tailored properties.
• Organic Synthesis & Catalysis: Serves as a valuable tool in academic and industrial research laboratories for constructing complex organic molecules and developing new catalytic processes.
• Surface Modification: Utilized to functionalize silica and other inorganic surfaces, altering their hydrophobicity and reactivity for specific applications.

Basic Information

Item	Details
Product Name	1,3-Diphenyl-1,1,3,3-Tetramethyldisilazane
CAS No.	8449-26-1
Molecular Formula	C16H23NSi2
Molecular Weight	285.54 g/mol
Synonyms	Bis(dimethylphenylsilyl)amine; 1,1,3,3-Tetramethyl-1,3-diphenyldisilazane; N,N-Bis(dimethylphenylsilyl)amine; Diphenyltetramethyldisilazane; Hexamethyldisilazane, 1,3-diphenyl-; HMDS, diphenyl derivative; Disilazane, 1,3-diphenyl-1,1,3,3-tetramethyl-
EINECS	Contact for details

Quality Control

Our 1,3-Diphenyl-1,1,3,3-Tetramethyldisilazane is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and supporting your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture ingress, which can degrade the product. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.