Description

Pristinamycine is a synergistic antibiotic complex belonging to the streptogramin class, primarily composed of Pristinamycin IA and Pristinamycin IIA. This compound is valued for its potent activity against Gram-positive bacteria, including multi-resistant strains like MRSA and VRE. It is a critical intermediate and active pharmaceutical ingredient (API) for the pharmaceutical industry, particularly in the development and manufacture of advanced antibiotic formulations. Global suppliers and manufacturers rely on high-purity Pristinamycine to ensure the efficacy and safety of finished drug products.

Application

• Pharmaceutical API Synthesis: Serves as the key active ingredient in the production of antibiotic drugs, particularly those targeting resistant bacterial infections.
• Veterinary Medicine: Used in formulations for treating bacterial infections in livestock and companion animals.
• Research & Development: Employed in microbiological and pharmacological research to study antibiotic mechanisms and resistance patterns.
• Reference Standard: Utilized as a high-purity standard in quality control laboratories for analytical method development and validation.
• Combination Therapy Development: Investigated for use in synergistic combination therapies to enhance antimicrobial efficacy and overcome resistance.

Basic Information

Product Name	Pristinamycine
CAS No.	8065-94-9
Molecular Formula	Mixture of C49H66N8O11 (IA) and C43H49N7O10 (IIA)
Molecular Weight	~ 934.0 (IA) and ~ 823.9 (IIA)
Synonyms	Pristinamycin; Streptogramin B; Vernamycin B; Staphylomycin; Pyostacine; Pristinamycins; Pristinamycine complex; Streptogramin A/B; Antibiotic UK-72051
EINECS	Contact for details

Quality Control

Our Pristinamycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and potency, meeting specifications suitable for pharmaceutical use. We provide full traceability and support regulatory submissions. Certificates of Analysis (COA) documenting results for assay, related substances, residual solvents, and microbiological purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0% (Total Pristinamycins)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%
Heavy Metals	≤ 20 ppm
Microbial Limits	Conforms to Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.