Description

Levonorgestrel is a potent second-generation synthetic progestin widely used in pharmaceutical applications. Its high biological activity and selectivity make it a critical active pharmaceutical ingredient (API) for hormonal therapies. This compound is essential for manufacturers in the global pharmaceutical industry, particularly for producing contraceptive and hormone replacement products.

Application

• Primary Active Pharmaceutical Ingredient (API) in various hormonal oral contraceptives.
• Key component in emergency contraceptive pills (commonly known as the "morning-after pill").
• Used in hormone-releasing intrauterine systems (IUDs) for long-term birth control.
• Incorporated into subdermal contraceptive implants for sustained drug delivery.
• Applied in hormone replacement therapy (HRT) regimens, often in combination with estrogens.
• Utilized in veterinary medicine for estrus synchronization in animals.
• Employed in clinical research and reference standard preparation.

Basic Information

Product Name	Levonorgestrel
CAS No.	8056-51-7
Molecular Formula	C₂₁H₂₈O₂
Molecular Weight	312.45 g/mol
Synonyms	D(-)-Norgestrel; LNG; (17α)-13-Ethyl-17-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one; 17α-Ethynyl-18-methyl-19-nortestosterone; Wy-5104; Norgestrel, Levonorgestrel; (-)-13β-Ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one
EINECS	Contact for details

Quality Control

Our Levonorgestrel is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Every batch undergoes comprehensive analytical testing including identity, purity, and impurity profile determination. A Certificate of Analysis (COA) detailing all test results is provided to ensure full traceability and regulatory compliance for our pharmaceutical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, protect from moisture. Keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Specific Optical Rotation	-30.0° to -35.0°
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 1.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	NMT 0.5%
Sulfated Ash	NMT 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.