Description

4,4,4-Trifluoro-1-(2-Naphthyl)-1,3-Butanedione is a specialized fluorinated diketone compound, serving as a high-value building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group and a naphthyl moiety, makes it a critical precursor for creating complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, as well as in materials science for creating specialty polymers and ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Coordination Chemistry & Catalysis: Acts as a versatile β-diketone ligand for chelating metal ions, useful in creating catalysts for asymmetric synthesis and luminescent materials.
• Advanced Material Precursor: Employed in the synthesis of organic semiconductors, metal-organic frameworks (MOFs), and other functional materials requiring precise fluorination.
• Chemical Research & Development: Serves as a standard or reagent in methodological studies for fluorination reactions and cross-coupling chemistry.

Basic Information

Product Name	4,4,4-Trifluoro-1-(2-Naphthyl)-1,3-Butanedione
CAS No.	893-33-4
Molecular Formula	C₁₄H₉F₃O₂
Molecular Weight	266.22 g/mol
Synonyms	2-Naphthoyltrifluoroacetone; 1,1,1-Trifluoro-4-(2-naphthyl)-2,4-butanedione; 4,4,4-Trifluoro-1-(naphthalen-2-yl)butane-1,3-dione; 2-Naphthyltrifluoroacetylacetone; TTA (2-Naphthyl); β-Diketone, 4,4,4-trifluoro-1-(2-naphthyl)-; 1-(2-Naphthyl)-4,4,4-trifluorobutane-1,3-dione
EINECS	213-000-9

Quality Control

Our 4,4,4-Trifluoro-1-(2-Naphthyl)-1,3-Butanedione is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment, and custom purity grades (e.g., >98%, >99%) are available to meet precise application needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, handling under subdued light is recommended for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.